The Hotel Mutiara Malioboro Yogyakarta is located in the Malioboro district of Yogyakarta, where many of the town's most popular and interesting shops are. The hotel is also nearby to government offices, cultural attractions, restaurants, and the Borobudur and Prambanan Temples. The hotel is also close to the Sultan Palace, the main train station, and the nearby international airport. The Hotel Mutiara Malioboro Yogyakarta is very close to the international airport, and it is a five minute walk from the Yogyakarta railway station. Guests can get around the hotel easily on foot and by bicycle, or they can hire horsecarts or pedicars to get around.

The rooms of the Hotel Mutiara Malioboro Yogyakarta feature beautiful attached marble bathrooms, and all the rooms are decorated in Javanese ethnic décor. The hotel's rooms also have lovely views of the surrounding city.

Guests of the Hotel Mutiara Malioboro Yogyakarta can enjoy plenty of modern amenities that cater to both business and pleasure travelers.